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首页> 外文OA文献 >Scientific Opinion on an application by Bayer CropScience and Monsanto (EFSA-GMO-NL-2009-75) for placing on the market of genetically modified glufosinate-ammonium- and glyphosate-tolerant oilseed rape MS8 × RF3 × GT73 and subcombinations, which have not been authorised previously (i.e. MS8 × GT73 and RF3 × GT73) independently of their origin, for food and feed uses, import and processing, with the exception of isolated seed protein for food, under Regulation (EC) No 1829/2003
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Scientific Opinion on an application by Bayer CropScience and Monsanto (EFSA-GMO-NL-2009-75) for placing on the market of genetically modified glufosinate-ammonium- and glyphosate-tolerant oilseed rape MS8 × RF3 × GT73 and subcombinations, which have not been authorised previously (i.e. MS8 × GT73 and RF3 × GT73) independently of their origin, for food and feed uses, import and processing, with the exception of isolated seed protein for food, under Regulation (EC) No 1829/2003

机译：关于拜耳作物科学和孟山都公司的申请（EFSA-GMO-NL-2009-75）的科学意见，该申请将耐草铵膦，草铵膦和草甘膦的转基因油菜籽MS8×RF3×GT73及其亚组合投放市场根据法规（EC）第1829/2003号，无论其来源如何，均已获得先前的批准（即MS8×GT73和RF3×GT73），用于食品和饲料的使用，进口和加工，但用于食品的分离的种子蛋白除外

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The EFSA Panel on Genetically Modified Organisms (GMO) previously assessed the three single events that are combined to produce the three-event stack oilseed rape (OSR) MS8 × RF3 × GT73. In this Scientific Opinion, the GMO Panel assessed the three-event stack OSR and subcombinations that have not been authorised previously (i.e. MS8 × GT73 and RF3 × GT73), independently of their origin, for food and feed uses, import and processing, with the exception of isolated seed protein for food. The combination of OSR events, MS8, RF3 and GT73, in the three-event stack OSR does not raise issues relating to molecular, agronomic/phenotypic or compositional characteristics requiring further investigations. In line with previous assessments and considering the scope of this application, the GMO Panel did not find indications of safety concern for food and feed with trace levels of glyphosate oxidoreductase (GOX)v247 protein derived from the three-event stack OSR; whereas, the GMO Panel cannot assess the safety of three-event stack OSR products rich in protein, such as rapeseed protein isolates in feed. As the risk assessment of the three-event stack OSR could not be completed for products rich in protein, such as rapeseed protein isolates, the GMO Panel is not in a position to complete the food and feed safety assessment of subcombinations within the scope of this application (i.e. MS8 × GT73 and RF3 × GT73). The two-event stack OSR MS8 × RF3 is outside the scope of this application. Considering the scope of this application, the mode of action of the introduced traits and the data available for the three-event and two-event stack OSR MS8 × RF3, the GMO Panel considered that different combinations of the events, MS8, RF3 and GT73, would not raise environmental concerns.
机译：EFSA转基因生物专家组（GMO）先前评估了三个单一事件，将三个单一事件相结合以产生三事件烟油菜（OSR）MS8×RF3×GT73。在此《科学意见》中，GMO小组评估了三事件堆栈OSR及其之前未经授权的子组合（即MS8×GT73和RF3×GT73），无论其来源如何，均用于食品和饲料用途，进口和加工。食品中分离的种子蛋白除外。三事件堆栈OSR中的OSR事件MS8，RF3和GT73的组合不会引起与分子，农艺/表型或组成特征相关的问题，需要进一步研究。根据先前的评估并考虑到本申请的范围，GMO专家组没有发现食品和饲料的安全性迹象，其痕量草甘膦氧化还原酶（GOX）v247蛋白来自三事件堆栈OSR；但是，GMO专家组无法评估富含蛋白质的三事件叠加OSR产品的安全性，例如饲料中的菜籽蛋白分离物。由于无法对富含蛋白质的产品（如菜籽蛋白分离物）完成三事件堆栈OSR的风险评估，因此GMO专家组无法在此范围内完成对亚组合食品和饲料安全性评估应用程序（即MS8×GT73和RF3×GT73）。两事件堆栈OSR MS8×RF3不在本应用程序范围内。考虑到此应用程序的范围，引入的特征的作用方式以及三事件和两事件堆栈OSR MS8×RF3的可用数据，GMO小组认为事件的不同组合MS8，RF3和GT73 ，不会引起环境问题。

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